I’ve been on Depakote 750mg for over 15 years and this medication has changed my life for the better. However, for some, it hasn’t been a good experience at all. This can be expected when taking different medications because your body will react differently to some than others. The problem happens when doctors try to push the medication too much by increasing the dosage instead of trying an alternative one. For example, doctors need to start you off at a low dose to get the medication into your blood. They should take this time to see how well you react to the medication. If you react well, the dose will be left as is, however, if you do not show improvement, then they’ll increase the dose. But, I believe there needs to be a limit to how much the doctors can increase the dose of any medication before stopping and trying an alternative instead.
Anyways, everyone is different and I’ve heard of doses up to 2250mg for some. These same people complained about muscle cramps, weight gain, decreased appetite and vomiting. You can read the user reviews on Depakote Divalproex in our community.